Overweight and Hypertension in Relation to Chronic Musculoskeletal Pain Among Community-Dwelling Adults: The Circulatory Risk in Communities Study (CIRCS)

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  • Kakihana Hironobu
    Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine
  • Jinnouchi Hiroshige
    Department of Hygiene and Public Health, Nippon Medical School Osaka Center for Cancer and Cardiovascular Disease Prevention
  • Kitamura Akihiko
    Osaka Center for Cancer and Cardiovascular Disease Prevention Research Team for Social Participation and Community Health, Tokyo Metropolitan Institute of Gerontology
  • Matsudaira Ko
    Department of Medical Research and Management for Musculoskeletal Pain, 22nd Century Medical & Research Center, Faculty of Medicine, the University of Tokyo
  • Kiyama Masahiko
    Osaka Center for Cancer and Cardiovascular Disease Prevention
  • Hayama-Terada Mina
    Osaka Center for Cancer and Cardiovascular Disease Prevention Yao City Public Health Center
  • Muraki Isao
    Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine
  • Kubota Yasuhiko
    Osaka Center for Cancer and Cardiovascular Disease Prevention
  • Yamagishi Kazumasa
    Department of Public Health Medicine, Faculty of Medicine, and Health Services Research and Development Center, University of Tsukuba
  • Okada Takeo
    Osaka Center for Cancer and Cardiovascular Disease Prevention
  • Imano Hironori
    Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine
  • Iso Hiroyasu
    Public Health, Department of Social Medicine, Osaka University Graduate School of Medicine Department of Public Health Medicine, Faculty of Medicine, and Health Services Research and Development Center, University of Tsukuba

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<p>Background: The association between overweight and chronic musculoskeletal pain may vary by anatomical site and be modified by hypertension status. This study examined the associations between overweight and low back and knee pains and their effect modification by hypertension status.</p><p>Methods: We conducted a community-based cross-sectional study involving 2,845 adults (1,080 men and 1,765 women) aged 40–89 years. Chronic knee pain (CKP) and low back pain (CLBP) lasting more than 3 months were categorized into more or less severe pain. Odds ratios (ORs) and 95% confidence intervals (CIs) of the association between overweight and more or less severe CKP and CLBP were determined using logistic regression and stratified by hypertension status. Adjustment variables were age, sex, area, hypertension, smoking and drinking status, inactivity, job category, mental stress, depression, and overall CKP or CLBP.</p><p>Results: Overall, 288 (10.1%) and 631 (22.2%) adults had more and less severe CKP, respectively, and 284 (10.0%) and 830 (29.2%) had more and less severe CLBP, respectively. Overweight was associated with overall CKP and more or less severe CKP, regardless of hypertension status. Overweight was not associated with overall CLBP; its association was more pronounced for more severe CLBP. The association between overweight and more severe CLBP was evident among non-hypertensives (multivariable OR 1.72; 95% CI, 1.09–2.71); however, that between overweight and less severe CLBP was not evident (multivariable OR 1.07; 95% CI, 0.73–1.56).</p><p>Conclusions: As hypertension may attenuate the association between overweight and CLBP, we should consider hypertension status for proper management of CLBP among overweight individuals.</p>

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