Effects of daily 1,000-IU vitamin D-fortified milk intake on skeletal muscle mass, power, physical function and nutrition status in Japanese

  • Matsuura Yasushi
    Kenshokai Gakuen College for Health and Welfare, Tokushima, Japan
  • Morishita Teruhiro
    Kenshokai Gakuen College for Health and Welfare, Tokushima, Japan
  • Sato Michiko
    Kenshokai Gakuen College for Health and Welfare, Tokushima, Japan
  • Sumida Nami
    Kenshokai Gakuen College for Health and Welfare, Tokushima, Japan
  • Katayama Takafumi
    Department of Statistics and Computer Science, College of Nursing Art and Science, University of Hyogo, Akashi, Japan
  • Tsutsumi Rie
    Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
  • Sakaue Hiroshi
    Department of Nutrition and Metabolism, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
  • Taketani Yutaka
    Department of Clinical Nutrition and Food Management, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
  • Sairyo Koichi
    Department of Orthopedics, Institute of Biomedical Sciences, Tokushima University Graduate School, Tokushima, Japan
  • Kawaura Akihiko
    Kenshokai Gakuen College for Health and Welfare, Tokushima, Japan
  • Takeda Eiji
    Kenshokai Gakuen College for Health and Welfare, Tokushima, Japan

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Abstract

<p>An intervention study was conducted to investigate the effects of daily 1,000-IU vitamin D-fortified milk intake on skeletal muscle mass, power, physical function and nutrition status in 26 healthy people and 8 older adults living in a nursing home. The serum 25-hydroxyvitamin D [25(OH)D] level was 13.4 ± 0.8 ng / mL and it markedly increased to 29.6 ± 0.9 ng / mL after daily 1000-IU vitamin D-fortified milk intake for 6 months. Handgrip strength (kg) also significantly increased in the 21-50 years and total groups, and male subjects, and the timed up and go test significantly improved in the 21-50 years and total groups, and female subjects after 6-month vitamin D intake. However, there were no significant differences between baseline and post-treatment in the Barthel Index (BI), walking speed (m / sec) or skeletal muscle mass (kg, % of BW, kg / m2). Therefore, the present study suggested that vitamin D-fortified milk intake is effective at improving muscle strength and physical function in Japanese, although further studies are needed, particularly for older adults. J. Med. Invest. 68 : 249-255, August, 2021</p>

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