Successful Early Immunosuppressive Therapy for Pulmonary Arterial Hypertension Due to Takayasu arteritis: Two Case Reports and a Review of Similar Case Reports in the English Literature
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- Suda Takuya
- Department of Rheumatology, Kanazawa University Graduate School of Medicine, Japan
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- Zoshima Takeshi
- Department of Rheumatology, Kanazawa University Graduate School of Medicine, Japan
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- Ito Kiyoaki
- Department of Rheumatology, Kanazawa University Graduate School of Medicine, Japan
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- Mizushima Ichiro
- Department of Rheumatology, Kanazawa University Graduate School of Medicine, Japan
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- Kawano Mitsuhiro
- Department of Rheumatology, Kanazawa University Graduate School of Medicine, Japan
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抄録
<p>The efficacy of early immunosuppressive therapy without invasive therapy, such as endovascular or surgical revascularization, for pulmonary hypertension due to Takayasu arteritis (TAK-PH) remains to be elucidated. We herein report two cases of TAK-PH due to pulmonary arteritis successfully treated with early immunosuppressive therapy. A literature review of 42 cases of TAK-PH with pulmonary artery involvement showed that the cases treated with immunosuppressive therapy early after the onset (within 12 months) had a higher erythrocyte sedimentation rate and better outcome without invasive therapy than those treated later. TAK-PH may be successfully treated with immunosuppressive therapy without invasive therapy when diagnosed early with high disease activity. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 61 (11), 1767-1774, 2022-06-01
一般社団法人 日本内科学会
