声門下に発生した粘表皮癌例

DOI Web Site Web Site 参考文献23件

書誌事項

タイトル別名
  • A Case of Subglottic Mucoepidermoid Carcinoma
  • セイモン カ ニ ハッセイ シタ ネンヒョウヒガンレイ

この論文をさがす

抄録

<p>We present, herein, a case report of subglottic mucoepidermoid carcinoma (MEC), with a review of the literature. A 56-year-old man presented to us with a two-month history of hoarseness and pharyngeal pain. Endoscopic examination showed fixation of the left vocal cord, and CT showed a tumor extending from the subglottic region to the left lobe of the thyroid. Since the subglottic region could not be observed directly through the laryngeal endoscope, fine-needle aspiration biopsy was performed through the left lobe of the thyroid; the result was “suspicious for squamous cell carcinoma (SCC).” PET-CT indicated left regional neck lymph node metastasis and distant metastasis in the right hilar lymph node and right gluteus minimus muscle. As the clinical stage was cT4bN2bM1, total pharyngo-laryngectomy and cervical esophagectomy, bilateral neck dissection, and reconstruction with a free jejunal graft were performed. Since the histopathological diagnosis was high-grade MEC, the patient received post-operative radiotherapy. At 4 months after the surgery, progression of the right hilar lymph node metastasis and new development of distant metastasis in the left ventricular heart muscle were detected, and the patient was given chemotherapy. However, the metastatic lesions failed to show treatment response despite several courses of chemotherapy. Furthermore, at 12 months after surgery, the patient developed disturbance of the left eye field because of a left choroid metastasis, and the other distant metastases had also worsened. The patient died of tracheal bleeding from the hilar lymph node metastasis at one year 11 months after surgery. Subglottic MEC is rare and only a few cases have been reported. It is often difficult to distinguish between MEC and SCC in the small tissue fragment obtained by biopsy. Although there is no standard treatment for MEC, surgery is the primary treatment and radiotherapy may be moderately effective.</p>

収録刊行物

参考文献 (23)*注記

もっと見る

関連プロジェクト

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ