Development and evolution of a primitive life-like molecular replication system

• Mizuuchi Ryo

  Komaba Institute for Science, The University of Tokyo JST, PRESTO

Bibliographic Information

Other Title

• 原始生命を模した分子複製システムの進化と改良

Abstract

  Origins-of-life hypotheses generally posit evolution from simple molecular replicators, such as RNA, to complex living systems. The understanding of how molecular replicators could have evolved on the early Earth has been advanced through theoretical research. However, experimental verification was generally hindered due to the lack of appropriate experimental systems (i.e., molecular replicators that can undergo Darwinian evolution). Here, I describe our recent approach to develop and evolve such a model replication system to illuminate possible evolutionary pathways that would have led to the emergence of complex life.

Journal

• Viva Origino

  Viva Origino 49 (3), 10-, 2021

  The Society for the Study of the Origin and Evolution of Life Japan

Keywords

• origins of life
• evolution
• replication
• diversification
• complexification
• parasites
• RNA
• liquid–liquid phase separation
• compartmentalization

Details

• CRID: 1390008998107659520
• NII Article ID: 130008130254
• DOI: 10.50968/vivaorigino.49_10
• ISSN: 13466933
• ISSN: 09104003
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Allowed