Antiresorptive Agent-related Osteonecrosis of the Jaw in the Elderly with Dementia and Breast Cancer: A Case Report

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  • IMAMACHI Kenji
    Dentistry and Oral Surgery, National Hospital Organization Hokkaido Cancer Center Oral Diagnosis and Oral Medicine, Department of Oral Pathobiological Science, Graduate School of Dental Medicine, Hokkaido University
  • HATA Hironobu
    Dentistry and Oral Surgery, National Hospital Organization Hokkaido Cancer Center
  • KAMAGUCHI Mayumi
    Oral Diagnosis and Oral Medicine, Department of Oral Pathobiological Science, Graduate School of Dental Medicine, Hokkaido University
  • KITAGAWA Yoshimasa
    Oral Diagnosis and Oral Medicine, Department of Oral Pathobiological Science, Graduate School of Dental Medicine, Hokkaido University

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  • 認知症の高齢乳癌患者に生じたARONJの1例
  • ニンチショウ ノ コウレイ ニュウガン カンジャ ニ ショウジタ ARONJ ノ 1レイ

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Abstract

We report a case of bone resorption inhibitor-related osteonecrosis of the jaw （ARONJ） in an 85-year-old woman with dementia and breast cancer. Although we initially selected conservative therapy, we switched to surgical therapy due to the progress of osteonecrosis. Prior to extensive sequestrectomy （sequestrectomy and surrounding bone shaving） under general anesthesia, it was necessary to solve various problems such as breast cancer control, underlying disease problems, and family cooperation. The postoperative course was favorable and no recurrence was noted until 15 months. It is expected that the number of elderly ARONJ patients with cancer and dementia will increase in the future. Therefore, oral surgeons should be able to collaborate with multiple occupations flexibly and appropriately.

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