Usefulness of Q-Probe PCR in Detecting Macrolide-Resistant <i>Mycoplasma pneumoniae</i> Infection in Children

• Muto Taichiro

  Department of Pediatrics, Aichi Medical University, Japan

• Nakamura Nami

  Department of Pediatrics, Aichi Medical University, Japan

• Masuda Yu

  Department of Pediatrics, Aichi Medical University, Japan

• Numoto Shingo

  Department of Pediatrics, Aichi Medical University, Japan

• Kodama Shunsuke

  Department of Pediatrics, Aichi Medical University, Japan

• Miyamoto Ryosuke

  Department of Pediatrics, Aichi Medical University, Japan

• Hayakawa Tomohito

  Department of Pediatrics, Aichi Medical University, Japan

• Mori Hiromitsu

  Department of Pediatrics, Aichi Medical University, Japan

• Iwayama Hideyuki

  Department of Pediatrics, Aichi Medical University, Japan

• Kurahashi Hirokazu

  Department of Pediatrics, Aichi Medical University, Japan

• Agata Hiroatsu

  Department of Pediatrics, Aichi Medical University, Japan

• Okumura Akihisa

  Department of Pediatrics, Aichi Medical University, Japan

Bibliographic Information

Other Title

• Usefulness of Q-Probe PCR in Detecting Macrolide-Resistant Mycoplasma pneumoniae Infection in Children

Abstract

To investigate the usefulness of quenching probe polymerase chain reaction (Q-probe PCR) for the detection of macrolide-resistant Mycoplasma pneumoniae (MP), we retrospectively analyzed the clinical course of 21 children with MP infection. The rate of macrolide-resistant MP was 66.7%. The duration of pyrexia after the initial antibiotic treatment was longer in patients with macrolide-resistant MP infection than in those with macrolide-sensitive MP infection. The duration of pyrexia after Q-probe PCR was not significantly different between patients with macrolide-resistant and -sensitive MP infection. Antibiotic use based on qPCR may reduce the duration of pyrexia. Q-probe PCR is useful in determining the appropriate antibiotics and improves the clinical course of MP infections.

Journal

• Japanese Journal of Infectious Diseases

  Japanese Journal of Infectious Diseases 75 (1), 89-91, 2021-01-31

  National Institute of Infectious Diseases, Japanese Journal of Infectious Diseases Editorial Committee

Keywords

• <i>Mycoplasma pneumoniae</i>
• Q-probe PCR
• antibiotics

Details

• CRID: 1390290846630674304
• NII Article ID: 130008143946
• NII Article ID: 40022816589
• NII Book ID: AA1132885X
• DOI: 10.7883/yoken.jjid.2021.003
• ISSN: 18842836
• ISSN: 13446304
• NDL BIB ID: 031961764
• PubMed: 34193662
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I031961764
• Web Site: https://www.jstage.jst.go.jp/article/yoken/75/1/75_JJID.2021.003/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2023054808
• Text Lang: en
• Data Source:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
  • KAKEN
• Abstract License Flag: Disallowed