Heterotopic Gastric Mucosa in Middle Esophagus Complicated with Esophageal Ulcers

  • Kishimoto Kenichi
    Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan
  • Shibagaki Kotaro
    Department of Endoscopy, Shimane University Hospital, Japan
  • Nonomura Saya
    Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan
  • Sumi Shohei
    Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan
  • Fukuda Naoki
    Fukuda Clinic, Japan
  • Takahashi Yusuke
    Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan
  • Kotani Satoshi
    Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan
  • Okimoto Eiko
    Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan
  • Oshima Naoki
    Department of Endoscopy, Shimane University Hospital, Japan
  • Kawashima Kousaku
    Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan
  • Ishimura Norihisa
    Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan
  • Ishihara Shunji
    Department of Gastroenterology, Faculty of Medicine, Shimane University, Japan

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抄録

<p>Heterotopic gastric mucosa (HGM) of esophagus, primarily occurring in cervical esophagus, is usually asymptomatic. A healthy woman (mid-40s) with postprandial heartburn was diagnosed with middle esophageal HGM and esophageal ulcers by esophagogastroduodenoscopy. Using 8-channel pH monitoring, a sensor near the HGM area detected postprandial acid phase (pH 3-4), while areas adjacent to the proximal and distal sensors were neutral, suggesting acid secretion from the HGM. A biopsy showed fundic gland tissue expressing H+/K+-ATPase and pepsinogen-I. Oral vonoprazan improved the clinical symptoms and endoscopic findings. This is the first report using 8-channel pH monitoring to diagnose extremely rare middle esophageal HGM. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 61 (18), 2735-2740, 2022-09-15

    一般社団法人 日本内科学会

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