Repeated Brain Magnetic Resonance Imaging Provides Clues for the Diagnosis of Autoimmune Glial Fibrillary Acid Protein Astrocytopathy
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- Natori Takahiro
- Department of Neurology, University of Yamanashi Hospital, Japan
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- Fukao Toko
- Department of Neurology, University of Yamanashi Hospital, Japan
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- Watanabe Tsubasa
- Department of Neurology, University of Yamanashi Hospital, Japan
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- Kurita Takafumi
- Department of Neurology, University of Yamanashi Hospital, Japan
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- Hata Takanori
- Department of Neurology, University of Yamanashi Hospital, Japan
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- Kimura Akio
- Department of Neurology, Gifu University Hospital, Japan
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- Shindo Kazumasa
- Department of Neurology, University of Yamanashi Hospital, Japan
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- Shimohata Takayoshi
- Department of Neurology, Gifu University Hospital, Japan
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- Takiyama Yoshihisa
- Department of Neurology, University of Yamanashi Hospital, Japan
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抄録
<p>We herein report a 47-year-old man with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP-A) revealed by periventricular radial linear enhancement on repeated brain magnetic resonance imaging (MRI). He presented with a history of headache and a fever followed by somnolence and worsening of consciousness. On admission (16 days from the onset), although lymphocytic pleocytosis and hypoglycorrhachia in the cerebrospinal fluid (CSF) were noted, initial brain MRI demonstrated non-specific findings. At 30 days from the onset, repeated brain MRI revealed characteristic findings of GFAP-A, and we detected anti-GFAP antibodies in the CSF. Thus, repeated brain MRI provides clues for the diagnosis of GFAP-A. </p>
収録刊行物
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- Internal Medicine
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Internal Medicine 61 (19), 2947-2950, 2022-10-01
一般社団法人 日本内科学会
