Postoperative Hypothyroidism After Hemithyroidectomy

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  • 甲状腺片葉切除術後の甲状腺機能低下症
  • コウジョウセンヘン ヨウ セツジョ ジュツゴ ノ コウジョウセン キノウ テイカショウ

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Abstract

<p>To determine the validity of surgical indications for thyroid diseases, we examined the incidence of postoperative hypothyroidism and possible factors inducing hypothyroidism in 23 patients who underwent hemithyroidectomy during the 5-year period from January 2016 to December 2020 at our department. To ascertain the risk factors for postoperative hypothyroidism, we evaluated the influences of the postoperative pathological diagnosis (benign or malignant), age, preoperative serum thyroid-stimulating hormone (TSH) level, and association of Hashimoto’s disease. Seven (30.4%) of the 23 patients developed postoperative hypothyroidism. Of the 23 patients, 15 (65.2%) and 8 (34.8%) patients were diagnosed by histopathology as having benign and malignant tumors, respectively. Four (17.4%) patients had association of Hashimoto’s disease. Our analysis revealed no significant association of the postoperative pathological diagnosis (benign vs. malignant), age, preoperative TSH level, or association of Hashimoto’s disease with the development of postoperative hypothyroidism. However, there appeared to be a tendency for patients with a high preoperative TSH level and those with association of Hashimoto’s disease to develop postoperative hypothyroidism. We considered that one of the 5 patients with benign tumors who developed postoperative hypothyroidism should have actually been followed up rather than having been treated by surgery. Surgical indications for benign tumors should be considered cautiously, taking into account the risk factors for the development of postoperative hypothyroidism.</p>

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