A questionnaire-based survey on the etiopathogenesis of chronic constipation during a medical check-up in Japan

• Otani Koji

  Department of Gastroenterology, Osaka City University Graduate School of Medicine

• Watanabe Toshio

  Department of Premier Preventive Medicine, Osaka City University Graduate School of Medicine

• Takahashi Kanae

  Department of Biostatistics, Hyogo College of Medicine

• Ominami Masaki

  Department of Gastroenterology, Osaka City University Graduate School of Medicine

• Nadatani Yuji

  Department of Premier Preventive Medicine, Osaka City University Graduate School of Medicine

• Fukunaga Shusei

  Department of Gastroenterology, Osaka City University Graduate School of Medicine

• Hosomi Shuhei

  Department of Gastroenterology, Osaka City University Graduate School of Medicine

• Kamata Noriko

  Department of Gastroenterology, Osaka City University Graduate School of Medicine

• Tanaka Fumio

  Department of Gastroenterology, Osaka City University Graduate School of Medicine

• Nagami Yasuaki

  Department of Gastroenterology, Osaka City University Graduate School of Medicine

• Taira Koichi

  Department of Gastroenterology, Osaka City University Graduate School of Medicine

• Kimura Tatsuo

  Department of Premier Preventive Medicine, Osaka City University Graduate School of Medicine

• Fukumoto Shinya

  Department of Premier Preventive Medicine, Osaka City University Graduate School of Medicine

• Fujiwara Yasuhiro

  Department of Gastroenterology, Osaka City University Graduate School of Medicine

抄録

The study group of the Japanese Society of Gastroenterology released evidence-based clinical practice guidelines for chronic constipation (CC) in 2017, and irritable bowel syndrome (IBS) was treated as one of the causes of CC. We examined the differences in characteristics between IBS and non-IBS subjects with CC who underwent a medical check-up in Japan. A total of 10,658 subjects participated in this study, and we focused on 467 subjects who fulfilled the diagnostic criteria of CC using a questionnaire survey. The number of IBS subjects was 21, and they had sleep disorders, were more symptomatic (e.g., abdominal pain, abdominal bloating/distension, feeling stressed, annoyance, lack of motivation, fatigue upon waking, and feeling depressed), and had more episodes of sensation of incomplete evacuation and anorectal obstruction/blockage during defecation than non-IBS subjects. Furthermore, stool frequency of IBS subjects was significantly different from non-IBS subjects. Multivariate ordinal logistic regression analysis revealed that the factors associated with a higher stool frequency were IBS [odds ratio (OR), 2.46; 95% confidence interval (CI), 1.00–6.05; p = 0.049], male sex (OR, 1.97; 95% CI, 1.20–3.23; p = 0.007), and regular exercise (OR, 1.80; 95% CI, 1.05–3.07; p = 0.033). These findings suggest that IBS has unique characteristics in subjects with CC.

収録刊行物

• Ｊｏｕｒｎａｌ　ｏｆ　Ｃｌｉｎｉｃａｌ　Ｂｉｏｃｈｅｍｉｓｔｒｙ　ａｎｄ　Ｎｕｔｒｉｔｉｏｎ

  Ｊｏｕｒｎａｌ　ｏｆ　Ｃｌｉｎｉｃａｌ　Ｂｉｏｃｈｅｍｉｓｔｒｙ　ａｎｄ　Ｎｕｔｒｉｔｉｏｎ 70 (2), 205-211, 2022

  一般社団法人　日本酸化ストレス学会

キーワード

• chronic constipation
• irritable bowel syndrome
• Rome IV
• stool frequency
• medical check-up

詳細情報

• CRID: 1390291767478119168
• NII論文ID: 130008165900
• DOI: 10.3164/jcbn.21-87
• ISSN: 18805086
• ISSN: 09120009
• Web Site: https://www.jstage.jst.go.jp/article/jcbn/70/2/70_21-87/_pdf
• Web Site: https://search.jamas.or.jp/link/ui/2023170039
• 本文言語コード: en
• データソース種別:
  • JaLC
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可