Recurrent Cerebral Infarcts Associated with Uterine Adenomyosis: Successful Prevention by Surgical Removal

  • Yasuda Manato
    Department of Neurology, Graduate School of Medicine, Chiba University, Japan
  • Yamanaka Yoshitaka
    Department of Neurology, Graduate School of Medicine, Chiba University, Japan
  • Kano Hiroki
    Department of Neurology, Graduate School of Medicine, Chiba University, Japan
  • Araki Nobuyuki
    Department of Neurology, Graduate School of Medicine, Chiba University, Japan
  • Ishikawa Hiroshi
    Department of Reproductive Medicine, Graduate School of Medicine, Chiba University, Japan
  • Ikeda Jun-ichiro
    Department of Diagnostic Pathology, Graduate School of Medicine, Chiba University, Japan
  • Kuwabara Satoshi
    Department of Neurology, Graduate School of Medicine, Chiba University, Japan

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抄録

<p>Hypercoagulability associated with malignant tumors causes thrombosis, termed Trousseau's syndrome, but is rarely associated with benign gynecological tumors, such as myoma and adenomyosis. We herein report a 47-year-old Japanese woman with uterine adenomyosis who developed multiple cerebral infarcts during menstruation. Edoxaban was initially used for prevention but failed to prevent recurrence of thrombosis. However, hysterectomy and bilateral salpingo-oophorectomy resulted in the successful prevention of recurrence of cerebral infarct for five years without antiplatelet or anticoagulant agents. In our patient, the surgical removal of adenomyosis was highly effective for preventing thrombosis in a patient with adenomyosis. </p>

収録刊行物

  • Internal Medicine

    Internal Medicine 61 (5), 735-738, 2022-03-01

    一般社団法人 日本内科学会

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