Characterization of reduced graphene oxide field-effect transistor and its application to biosensor

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<jats:p>We confirmed the specific detection of immunoglobulin E (IgE) using an aptamer-immobilized reduced graphene oxide (rGO) field effect transistor (FET). The detection limit and dynamic range were estimated to be 8.1 ng/ml and 10<jats:sup>4</jats:sup>, respectively. These characteristics are comparable with these of current fluorescent markers. Although the mobility of rGO-FET was around 6 cm<jats:sup>2</jats:sup> V<jats:sup>−1</jats:sup> s<jats:sup>−1</jats:sup>, which is two to three orders lower than that of mechanically exfoliated pristine graphene FET, its sensitivity to IgE was only one order lower than that of pristine graphene FET.</jats:p>

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