Image sensor with hybrid emission filter for in vivo fluorescent imaging

  • Kiyotaka Sasagawa
    Division of Materials Science Graduate School of Science and Technology Nara Institute of Science and Technology Nara Japan
  • Erus Rustami
    Division of Materials Science Graduate School of Science and Technology Nara Institute of Science and Technology Nara Japan
  • Yasumi Ohta
    Division of Materials Science Graduate School of Science and Technology Nara Institute of Science and Technology Nara Japan
  • Makito Haruta
    Division of Materials Science Graduate School of Science and Technology Nara Institute of Science and Technology Nara Japan
  • Hironari Takehara
    Division of Materials Science Graduate School of Science and Technology Nara Institute of Science and Technology Nara Japan
  • Hiroyuki Tashiro
    Division of Materials Science Graduate School of Science and Technology Nara Institute of Science and Technology Nara Japan
  • Jun Ohta
    Division of Materials Science Graduate School of Science and Technology Nara Institute of Science and Technology Nara Japan

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<jats:title>Abstract</jats:title><jats:p>In this paper, we report a method of fabricating an implantable image sensor equipped a bandpass hybrid filter for highly sensitive fluorescence observation. A hybrid filter that combines an interference filter and an absorption filter enables a high excitation light removal performance in an implantable image sensor that does not use a lens. In this study, a thin hybrid filter was successfully mounted on the image sensor using the transfer method by using a laser lift‐off technique. The transferred filter has no crack. It was demonstrated that the prototype device exhibited high excitation light removal performance and was able to acquire a fluorescent image with high contrast.</jats:p>

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