Benign myoclonus of early infancy

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<jats:title>Abstract</jats:title><jats:p>Sixteen infants, aged 3 to 81/2 months, were studied close to the onset of a myoclonic syndrome akin to that normally called <jats:italic>infantile spasms</jats:italic> with hypsarrhythmia. None were found to have the clinical and laboratory characteristics common to the syndrome, however: none showed regression or arrest in their neurological/developmental status, nor did their EEG ever develop a hypsarrhythmic or other abnormal pattern. All were followed for a minimum of 18 months to a maximum of nine years. In all patients the myoclonus stopped early, in none persisting after the age of 2 years, and no other seizure phenomena have so far evolved in any of these infants. This favorable outcome occurred in those who were treated as well as those who were not. The self‐limited course of this condition is emphasized within the context of the more unusual myoclonic syndromes of early and late infancy.</jats:p>

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