Precise characterization and quantification of infantile spasms
Abstract
<jats:title>Abstract</jats:title><jats:p>With the use of a time‐synchronized video and polygraphic recording system, 5,042 infantile spasms were monitored and analyzed in 24 infants aged 1 to 43 months. Of these, 33.9% were flexor, 22.5% extensor, and 42.0% mixed flexor‐extensor. Sometimes the spasms were followed by a period of akinesia and diminished responsiveness lasting up to 90 seconds, and rarely (1.0%) this “arrest” effect constituted the entire seizure. More than one type of seizure occurred in 21 of the 24 infants. In the same number, 78.3% of the seizures occurred in clusters, and the intensity and frequency of the spasms in each cluster often increased to a peak, then progressively decreased until they stopped. Predominantly, the clusters occurred soon after arousal from sleep. The number of seizures occurring at night (55.2%) was similar to the diurnal number (44.8%). The electroencephalographic seizure pattern was variable, but a marked generalized attenuation of electrical activity was a feature of 71.7% of the attacks. Attenuation episodes of similar degree and duration occurred with no evidence of a seizure.</jats:p>
Journal
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- Annals of Neurology
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Annals of Neurology 6 (3), 214-218, 1979-09
Wiley
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Keywords
Details 詳細情報について
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- CRID
- 1364233271166479104
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- NII Article ID
- 30008837538
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- ISSN
- 15318249
- 03645134
- http://id.crossref.org/issn/03645134
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- Data Source
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- Crossref
- CiNii Articles