PEGylation of Poly(ethylene imine) Affects Stability of Complexes with Plasmid DNA under in Vivo Conditions in a Dose-Dependent Manner after Intravenous Injection into Mice

  • Thomas Merdan
    Department of Pharmaceutics and Biopharmacy, Philipps-University of Marburg, Ketzerbach 63 , D-35032 Marburg, Germany, Department of Physiology, Philipps-University of Marburg, Pilgrimstein, D-35037 Marburg, Germany, Department of Pharmaceutics and Pharmaceutical Chemistry, The University of Utah, 30 South, 2000 East, Salt Lake City, Utah 84112.
  • Klaus Kunath
    Department of Pharmaceutics and Biopharmacy, Philipps-University of Marburg, Ketzerbach 63 , D-35032 Marburg, Germany, Department of Physiology, Philipps-University of Marburg, Pilgrimstein, D-35037 Marburg, Germany, Department of Pharmaceutics and Pharmaceutical Chemistry, The University of Utah, 30 South, 2000 East, Salt Lake City, Utah 84112.
  • Holger Petersen
    Department of Pharmaceutics and Biopharmacy, Philipps-University of Marburg, Ketzerbach 63 , D-35032 Marburg, Germany, Department of Physiology, Philipps-University of Marburg, Pilgrimstein, D-35037 Marburg, Germany, Department of Pharmaceutics and Pharmaceutical Chemistry, The University of Utah, 30 South, 2000 East, Salt Lake City, Utah 84112.
  • Udo Bakowsky
    Department of Pharmaceutics and Biopharmacy, Philipps-University of Marburg, Ketzerbach 63 , D-35032 Marburg, Germany, Department of Physiology, Philipps-University of Marburg, Pilgrimstein, D-35037 Marburg, Germany, Department of Pharmaceutics and Pharmaceutical Chemistry, The University of Utah, 30 South, 2000 East, Salt Lake City, Utah 84112.
  • Karl Heinz Voigt
    Department of Pharmaceutics and Biopharmacy, Philipps-University of Marburg, Ketzerbach 63 , D-35032 Marburg, Germany, Department of Physiology, Philipps-University of Marburg, Pilgrimstein, D-35037 Marburg, Germany, Department of Pharmaceutics and Pharmaceutical Chemistry, The University of Utah, 30 South, 2000 East, Salt Lake City, Utah 84112.
  • Jindrich Kopecek
    Department of Pharmaceutics and Biopharmacy, Philipps-University of Marburg, Ketzerbach 63 , D-35032 Marburg, Germany, Department of Physiology, Philipps-University of Marburg, Pilgrimstein, D-35037 Marburg, Germany, Department of Pharmaceutics and Pharmaceutical Chemistry, The University of Utah, 30 South, 2000 East, Salt Lake City, Utah 84112.
  • Thomas Kissel
    Department of Pharmaceutics and Biopharmacy, Philipps-University of Marburg, Ketzerbach 63 , D-35032 Marburg, Germany, Department of Physiology, Philipps-University of Marburg, Pilgrimstein, D-35037 Marburg, Germany, Department of Pharmaceutics and Pharmaceutical Chemistry, The University of Utah, 30 South, 2000 East, Salt Lake City, Utah 84112.

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