Airway Remodeling in Asthma: Therapeutic Implications of Mechanisms

  • Robert J. Homer
    Department of Pathology, Yale University School of Medicine, New Haven; and Pathology and Laboratory Medicine Service, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut
  • Jack A. Elias
    Section of Pulmonary and Critical Care Medicine, Yale University School of Medicine, New Haven, Connecticut

抄録

<jats:p>Asthma is currently recognized as a chronic inflammatory disorder of the airways that leads to tissue injury and subsequent structural changes collectively called airway remodeling. Transgenic modeling of inflammatory mediators allows for the discovery of unexpected effects, dissection of downstream signaling events, and clues to future therapies.</jats:p>

収録刊行物

  • Physiology

    Physiology 20 (1), 28-35, 2005-02

    American Physiological Society

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