Bone resorbing activity of purified capsular material from Actinobacillus actinomycetemcomitans
抄録
<jats:p>Capsular material (CM) from <jats:italic>Actinobacillus actinomycetemcomitans</jats:italic> was extracted with saline and purified by gel filtration and ionexchange chromatography. Preliminary chemical analysis of the purified material indicated that it may be a glycoprotein. The CM was found to be a potent mediator of bone resorption, active at concentrations one thousand‐fold lower than lipopolysaccharide from the same organism, and its action was inhibited by indomethacin. CM must therefore be considered an additional potential mediator of bone resorption in periodontal disease.</jats:p>
収録刊行物
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- Journal of Periodontal Research
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Journal of Periodontal Research 20 (5), 484-491, 1985-09
Wiley
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詳細情報 詳細情報について
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- CRID
- 1363107371354519936
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- NII論文ID
- 30013418329
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- ISSN
- 16000765
- 00223484
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- データソース種別
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