抄録
<jats:p>In an asymptomatic 4 yr old child with radiographic evidence of parenchymal lung disease, bronchoalveolar lavage (BAL) yielded the diagnosis of chronic lipid pneumonia caused by chronic aspiration of mineral oil given as a laxative. BAL analysis showed a marked reduction in the total number of alveolar macrophages; almost 70% of these cells contained intracytoplasmic lipid vacuoles. It also disclosed lymphocytic (cytotoxic/suppressor) alveolitis. A high percentage of lymphocytes expressed antigen markers of activation (human leucocyte antigen (HLA)-DR), CD54 and CD25). BAL analysis 18 months after mineral oil intake revealed that lymphocytes bearing antigen markers of activation had markedly decreased whereas alveolar macrophages (normal and lipid-laden) had increased. A subsequent whole lung BAL was considered unnecessarily invasive in this otherwise healthy child.</jats:p>
収録刊行物
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- European Respiratory Journal
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European Respiratory Journal 11 (1), 239-242, 1998-01-01
European Respiratory Society (ERS)
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詳細情報 詳細情報について
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- CRID
- 1364233270239482496
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- NII論文ID
- 30013491406
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- ISSN
- 13993003
- 09031936
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- データソース種別
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- Crossref
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