The outer membrane protein, Antigen 43, mediates cell‐to‐cell interactions within <i>Escherichia coli</i> biofilms

DOI Web Site Web Site 被引用文献2件

この論文をさがす

抄録

<jats:p>Transcription of the <jats:italic>agn43</jats:italic> locus, which specifies an outer membrane protein of <jats:italic>Escherichia coli</jats:italic>, is regulated in a phase‐variable fashion by the OxyR–DNA binding protein and Dam methylase. Despite its well‐characterized regulation, the function of Ag43 has remained elusive until now. Previous studies indicated that Ag43 mediates autoaggregation of certain strains of <jats:italic>E. coli</jats:italic> in liquid culture. Given this phenotype, we examined the role of Ag43 in biofilm formation. Here, we report that Ag43 contributes to <jats:italic>E. coli</jats:italic> biofilm formation in glucose‐minimal medium, but not in Luria–Bertani broth. In addition, we show that flagellar‐mediated motility is required for biofilm formation in both rich and minimal environments. Altogether, our results suggest that <jats:italic>E. coli</jats:italic> uses both common and specific gene sets for the development of biofilms under various growth conditions.</jats:p>

収録刊行物

被引用文献 (2)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ