Identification of an Antigen from Normal Human Tissue That Crossreacts with the Carcinoembryonic Antigen

• S. Von Kleist

  Laboratoire d'Immunochimie, Institut de Recherches Scientifiques sur le Cancer, B.P. 8, 94 Villejuif, France

• G. Chavanel

  Laboratoire d'Immunochimie, Institut de Recherches Scientifiques sur le Cancer, B.P. 8, 94 Villejuif, France

• P. Burtin

  Laboratoire d'Immunochimie, Institut de Recherches Scientifiques sur le Cancer, B.P. 8, 94 Villejuif, France

抄録

A glycoprotein present in normal human tissue is characterized that is neither organ- nor tumor-specific (nonspecific crossreacting antigen) and that crossreacts (by the Ouchterlony double-diffusion technique) with the carcinoembryonic antigen. This immunological relationship indicates common determinants on the molecules of both antigens. We demonstrate that the nonspecific crossreacting antigen is not a fragment of the carcinoembryonic antigen molecule.

収録刊行物

• Proceedings of the National Academy of Sciences

  Proceedings of the National Academy of Sciences 69 (9), 2492-2494, 1972-09

  Proceedings of the National Academy of Sciences

キーワード

• Multidisciplinary

詳細情報

• CRID: 1360011143526278016
• NII論文ID: 30016259892
• DOI: 10.1073/pnas.69.9.2492
• ISSN: 10916490
• ISSN: 00278424
• Web Site: https://pnas.org/doi/pdf/10.1073/pnas.69.9.2492
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