Fetal cells in the blood of pregnant women: detection and enrichment by fluorescence-activated cell sorting.

• L A Herzenberg

• D W Bianchi

• J Schröder

• H M Cann

• G M Iverson

抄録

Fetal cells, potentially usable for prenatal diagnosis, were sorted from maternal blood samples taken as early as 15 weeks of gestation. Immunogenetic and cytogenic criteria established the fetal origin of the observed cells: Y-chromatin-containing (male) cells were detected in the sorted sample if and only if the newborn proved to be male and carried cell-surface antigens detected by the fluorescent-labeled antibody used for sorting with the fluorescence-activated cell sorter.

収録刊行物

• Proceedings of the National Academy of Sciences

  Proceedings of the National Academy of Sciences 76 (3), 1453-1455, 1979-03

  Proceedings of the National Academy of Sciences

キーワード

• Multidisciplinary

詳細情報

• CRID: 1363670318539477120
• NII論文ID: 30016268662
• DOI: 10.1073/pnas.76.3.1453
• ISSN: 10916490
• ISSN: 00278424
• ISSN: http://id.crossref.org/issn/00278424
• Web Site: https://pnas.org/doi/pdf/10.1073/pnas.76.3.1453
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