STUDIES ON SCRUB TYPHUS (TSUTSUGAMUSHI DISEASE)

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  • Fred L. Rights
    From the Department of Virus and Rickettsial Diseases, Army Medical Department Research and Graduate School, Washington, D. C., and the Department of Bacteriology, College of Physicians and Surgeons, Columbia University, New York
  • Joseph E. Smadel
    From the Department of Virus and Rickettsial Diseases, Army Medical Department Research and Graduate School, Washington, D. C., and the Department of Bacteriology, College of Physicians and Surgeons, Columbia University, New York

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<jats:p>Antigenic differences among strains of R. tsutsugamushi are sufficiently great that vaccines prepared from certain strains fail to induce resistance in mice to infection with other strains. Although the results of cross-vaccination tests indicate varying degrees of relationship between a number of the strains, there is no correlation between source of the rickettsia and antigenic pattern of the agent.</jats:p>

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