Phosphorelay and Transcription Control in Cytokinin Signal Transduction

  • Jen Sheen
    Department of Genetics, Harvard Medical School and Department of Molecular Biology, Massachusetts General Hospital, Boston, MA 02114, USA.

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<jats:p> The past decade has seen substantial advances in knowledge of molecular mechanisms and actions of plant hormones, but only in the past few years has research on cytokinins begun to hit its stride. Cytokinins are master regulators of a large number of processes in plant development, which is known to be unusually plastic and adaptive, as well as resilient and perpetual. These characteristics allow plants to respond sensitively and quickly to their environments. Recent studies have demonstrated that cytokinin signaling involves a multistep two-component signaling pathway, resulting in the development of a canonical model of cytokinin signaling that is likely representative in plants. This Viewpoint outlines this general model, focusing on the specific example of <jats:italic>Arabidopsis</jats:italic> , and introduces the STKE Connections Maps for both the canonical module and the specific <jats:italic>Arabidopsis</jats:italic> Cytokinin Signaling Pathway. </jats:p>

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  • Science

    Science 296 (5573), 1650-1652, 2002-05-31

    American Association for the Advancement of Science (AAAS)

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