Enhanced Protein Synthesis in a Cell-Free System from Hypertrophied Skeletal Muscle

DOI Web Site 被引用文献1件
  • M. Hamosh
    Laboratory of General and Comparative Biochemistry, National Institute of Mental Health, Bethesda, Maryland 20014
  • M. Lesch
    Laboratory of General and Comparative Biochemistry, National Institute of Mental Health, Bethesda, Maryland 20014
  • J. Baron
    Laboratory of General and Comparative Biochemistry, National Institute of Mental Health, Bethesda, Maryland 20014
  • S. Kaufman
    Laboratory of General and Comparative Biochemistry, National Institute of Mental Health, Bethesda, Maryland 20014

抄録

<jats:p> Hypertrophy of the rat soleus muscle was induced by tenotomy of the synergistic muscles. Four days after the operation, the weight of the muscle had increased by 30 percent. The hypertrophied muscle had an increased concentration of DNA and RNA, when compared to the contralateral control soleus. Although the amount of myofibrillar protein increased during the 4-day period, the concentration of this component decreased. Microsomes prepared from hypertrophied muscle had an increased RNA concentration. The combined microsomes and <jats:italic>p</jats:italic> H-5 enzyme from hypertrophied muscle supported a faster rate of protein synthesis in vitro than the same system prepared from an equal weight of contralateral muscle which was used as a control. </jats:p>

収録刊行物

  • Science

    Science 157 (3791), 935-937, 1967-08-25

    American Association for the Advancement of Science (AAAS)

被引用文献 (1)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ