Endocrine Pancreas: Three-Dimensional Reconstruction Shows Two Types of Islets of Langerhans

DOI Web Site 被引用文献13件
  • D. Baetens
    Institute of Histology and Embryology, University of Geneva Medical School, 1211 Geneva 4, Switzerland
  • F. Malaisse-Lagae
    Institute of Histology and Embryology, University of Geneva Medical School, 1211 Geneva 4, Switzerland
  • A. Perrelet
    Institute of Histology and Embryology, University of Geneva Medical School, 1211 Geneva 4, Switzerland
  • L. Orci
    Institute of Histology and Embryology, University of Geneva Medical School, 1211 Geneva 4, Switzerland

抄録

<jats:p>Three-dimensional reconstructions of islets of Langerhans, based on immunofluorescent staining of successive serial sections with antiserums to insulin, glucagon, somatostatin, and pancreatic polypeptide reveal a marked difference in the number of cells containing glucagon and pancreatic polypeptide depending on the anatomical location of the islet in the pancreas. The two types of islets are situated in regions of exocrine tissue that are drained by different excretory ducts. This demonstration contradicts the assumption that all islets in the pancreas are similar in their endocrine cell content.</jats:p>

収録刊行物

  • Science

    Science 206 (4424), 1323-1325, 1979-12-14

    American Association for the Advancement of Science (AAAS)

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