Isolation and Transmission of Human Retrovirus (Human T-Cell Leukemia Virus)

DOI Web Site 被引用文献13件
  • M. Popovic
    Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, Maryland 20205
  • P. S. Sarin
    Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, Maryland 20205
  • M. Robert-Gurroff
    Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, Maryland 20205
  • V. S. Kalyanaraman
    Department of Cell Biology, Litton Bionetics, Inc., Kensington, Maryland 20895
  • D. Mann
    Division of Cancer Biology and Diagnosis, National Cancer Institute, Bethesda, Maryland 20205
  • J. Minowada
    Department of Immunology, Roswell Park Memorial Institute, Buffalo, New York 14263
  • R. C. Gallo
    Laboratory of Tumor Cell Biology, National Cancer Institute, Bethesda, Maryland 20205

抄録

<jats:p>Nine new isolates of human T-cell leukemia-lymphoma virus (HTLV) were obtained from cells of seven patients with malignancies of mature T cells and from two clinically normal relatives of a T-cell leukemia patient. These people were from the United States, Israel, the West Indies, and Japan. The virus was detected in the fresh T cells and was isolated from the established T-cell lines. Each isolate is closely related to the first HTLV isolate, and all the new HTLV isolates were transmitted into normal human T cells obtained from the umbilical cord blood of newborns.</jats:p>

収録刊行物

  • Science

    Science 219 (4586), 856-859, 1983-02-18

    American Association for the Advancement of Science (AAAS)

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