Multiple Representations of Pain in Human Cerebral Cortex

  • Jeanne D. Talbot
    Laboratoire de neurophysiologie comportementale, Faculté de médecine dentaire, Université de Montréal, Quebec, Canada H3C 3J7.
  • Sean Marrett
    Positron Imaging Laboratories, McConnell Brain Imaging Center, Montreal Neurological Institute, Montreal, Quebec, Canada H3A 2B4.
  • Alan C. Evans
    Positron Imaging Laboratories, McConnell Brain Imaging Center, Montreal Neurological Institute, Montreal, Quebec, Canada H3A 2B4.
  • Ernst Meyer
    Positron Imaging Laboratories, McConnell Brain Imaging Center, Montreal Neurological Institute, Montreal, Quebec, Canada H3A 2B4.
  • M. Catherine Bushnell
    Laboratoire de neurophysiologie comportementale, Faculté de médecine dentaire, Université de Montréal, Quebec, Canada H3C 3J7.
  • Gary H. Duncan
    Laboratoire de neurophysiologie comportementale, Faculté de médecine dentaire, Université de Montréal, Quebec, Canada H3C 3J7.

抄録

<jats:p>The representation of pain in the cerebral cortex is less well understood than that of any other sensory system. However, with the use of magnetic resonance imaging and positron emission tomography in humans, it has now been demonstrated that painful heat causes significant activation of the contralateral anterior cingulate, secondary somatosensory, and primary somatosensory cortices. This contrasts with the predominant activation of primary somatosensory cortex caused by vibrotactile stimuli in similar experiments. Furthermore, the unilateral cingulate activation indicates that this forebrain area, thought to regulate emotions, contains an unexpectedly specific representation of pain.</jats:p>

収録刊行物

  • Science

    Science 251 (4999), 1355-1358, 1991-03-15

    American Association for the Advancement of Science (AAAS)

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