Contribution of Sialic Acid-Binding Adhesin to Pathogenesis of Experimental Endocarditis Caused by <i>Streptococcus gordonii</i> DL1

• Yukihiro Takahashi

  Department of Microbiology

• Eizo Takashima

  Department of Microbiology

• Kisaki Shimazu

  Department of Pediatric Dentistry

• Hisao Yagishita

  Department of Pathology, Nippon Dental University School of Dentistry at Tokyo, 1-9-20 Fujimi, Chiyoda-ku, Tokyo 102-8159, Japan

• Takaaki Aoba

  Department of Pathology, Nippon Dental University School of Dentistry at Tokyo, 1-9-20 Fujimi, Chiyoda-ku, Tokyo 102-8159, Japan

• Kiyoshi Konishi

  Department of Microbiology

抄録

An insertional mutation in hsa , the gene encoding the sialic acid-binding adhesin of Streptococcus gordonii DL1, resulted in a significant reduction of the infection rate of the organism and an inflammatory reaction in the rat aortic valve with experimental endocarditis, suggesting that the adhesin contributes to the infectivity of the organism for heart valves.

収録刊行物

• Infection and Immunity

  Infection and Immunity 74 (1), 740-743, 2006-01

  American Society for Microbiology

キーワード

• Infectious Diseases
• Immunology
• Microbiology
• Parasitology

詳細情報

• CRID: 1363388845308998528
• NII論文ID: 30020833040
• DOI: 10.1128/iai.74.1.740-743.2006
• ISSN: 10985522
• ISSN: 00199567
• Web Site: https://journals.asm.org/doi/pdf/10.1128/IAI.74.1.740-743.2006
• データソース種別:
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  • CiNii Articles