Ultrasonic Visualization of Still and Flowing Waters Using Contrast Agents of Magnetite-Encapsulated Porous Silica Microspheres.

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  • Zhang Minjuan
    Department of Physical Electronics, Tokyo Institute of Technology, O–okayama, Meguro–ku, Tokyo 152, Japan
  • Itoh Tomoyuki
    Department of Physical Electronics, Tokyo Institute of Technology, O–okayama, Meguro–ku, Tokyo 152, Japan
  • Abe Masanori
    Department of Physical Electronics, Tokyo Institute of Technology, O–okayama, Meguro–ku, Tokyo 152, Japan

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  • Ultrasonic Visualization of Still and F

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Porous silica microspheres, ~ 2.2 µ m in average diameter, were encapsulated with magnetite ( Fe3O4) by ferrite plating in an aqueous solution of FeCl2 at 65°C. Using the resultant ferrite-encapsulated particles as ultrasonographic contrast agents (in which air trapped in the pores scatters ultrasonic waves), we tried to visualize still and flowing waters in holes and a channel perforated in agar blocks using a 7.5 MHz B-mode echograph. Clear image enhancement was successfully obtained only when the ferrite-encapsulated particles were evaporated before they were dispersed in the water. This is because during ferrite plating in the aqueous solution the pores were permeated with water, which was expelled by evaporation, and then substituted by air when the particles were again exposed to air.

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