On-Pump Versus Off-Pump Coronary Artery Bypass Surgery in a Matched Sample of Women

  • Michael J. Mack
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.
  • Phillip Brown
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.
  • Frank Houser
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.
  • Mark Katz
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.
  • Aaron Kugelmass
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.
  • April Simon
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.
  • Salvatore Battaglia
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.
  • Lynn Tarkington
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.
  • Steven Culler
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.
  • Edmund Becker
    From HCA, Inc (M.J.M., P.B., F.H., M.K., A.K., S.B., L.T.), Nashville, Tenn; Cardiac Data Solutions, Inc (A.S.), Zionsville, Ind; and Rollins School of Public Health at Emory University (S.C., E.B.), Atlanta, Ga.

書誌事項

タイトル別名
  • A Comparison of Outcomes

抄録

<jats:p> <jats:bold> <jats:italic>Background—</jats:italic> </jats:bold> Women have consistently higher mortality and morbidity than men after coronary artery bypass grafting (CABG). Whether elimination of cardiopulmonary bypass and performance of coronary artery bypass grafting off-pump (OPCAB) have a beneficial effect specifically in women has not been defined. </jats:p> <jats:p> <jats:bold> <jats:italic>Methods and Results—</jats:italic> </jats:bold> From January 1998 through March 2002, 21 902 consecutive female patients at 82 hospitals underwent isolated CABG, as reported in an administrative database. Propensity score computer matching was performed based on 13 variables representing patient characteristics and preoperative risk factors to correct for and minimize selection bias. A total of 7376 (3688 pairs) women undergoing CABG surgery were able to be successfully matched. In a propensity score computer-matched cohort, multivariate logistic regression (odds ratio) revealed that women undergoing on-pump surgery had a 73.3% higher mortality ( <jats:italic>P</jats:italic> =0.002) and a 47.2% higher risk of bleeding complications ( <jats:italic>P</jats:italic> =0.019). </jats:p> <jats:p> <jats:bold> <jats:italic>Conclusions—</jats:italic> </jats:bold> In a retrospective analysis of women undergoing CABG, computer-matched to minimize selection bias, off-pump surgery led to decreased mortality and morbidity including bleeding complications. </jats:p>

収録刊行物

  • Circulation

    Circulation 110 (11_suppl_1), 2004-09-14

    Ovid Technologies (Wolters Kluwer Health)

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