Development and Reversal of a Proteoglycan Aggregation Defect In Normal Canine Knee Cartilage After Immobilization
抄録
<jats:title>Abstract</jats:title><jats:p>Healthy adult dogs were studied for a defect in proteoglycan aggregation by immobilizing one limb for varying periods of time. Immobilization for 6 days resulted in a 41% reduction in proteoglycan synthesis by articular cartilage from the restrained knee compared with the contralateral control knee. After 3 weeks of immobilization, proteoglycan aggregation was no longer demonstrable in cartilage from the constrained limb. The aggregation defect was rapidly reversible and aggregates were again normal size 2 weeks after removal of a cast that had been worn for 6 weeks.</jats:p>
収録刊行物
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- Arthritis & Rheumatism
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Arthritis & Rheumatism 22 (5), 508-517, 1979-05
Wiley
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詳細情報 詳細情報について
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- CRID
- 1363388845864285312
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- NII論文ID
- 30025716971
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- ISSN
- 15290131
- 00043591
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- データソース種別
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