Poorly Differentiated Carcinomas of the Thyroid Gland

DOI Web Site 被引用文献3件
  • Manuel Sobrinho-Simoes
  • Clara Sambade
  • Elsa Fonseca
    Institute of Molecular Pathology and Immunology of the University ofPorto-IPATIMUP, Porto, Portugal; Department of Pathology, Medical Faculty of Porto, Porto, Portugal; Department of Pathology, Hospital S. Joao, Porto, Portugal
  • Paula Soares
    Institute of Molecular Pathology and Immunology of the University ofPorto-IPATIMUP, Porto, Portugal; Department of Pathology, Medical Faculty of Porto, Porto, Portugal

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タイトル別名
  • A Review of the Clinicopathologic Features of a Series of 28 Cases of a Heterogeneous, Clinically Aggressive Group of Thyroid Tumors

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<jats:p> We evaluated the clinicopathologic, immunohistochemical, lectin histochemical, ultrastructural and morphometric characteristics of a series of 28 poorly differentiated carcinomas of the thyroid (PDCT). The 28 tumors were classified according to their predominant growth pattern as insular (n=12), trabecular (n=10) and solid subtypes (n=6). The overall mortality rate was 46%. No significant differences were found among the 3 subtypes. Data obtained by lectin histochemistry, electron microscopy, and morphometry point to a closer relationship of PDCT to follicular than to papillary carcinoma. Our results do not support the subdivision of PDCT into subtypes. </jats:p>

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