Antibody Response Determined with Antibody‐Dependent Cell‐Mediated Cytotoxicity (ADCC), Neutralizing Antibody, and Varicella Skin Test in Children with Natural Varicella and After Varicella Immunization

• Toshiaki Ihara

• Takashi Kato

• Sadayoshi Torigoe

• Kaichi Oitani

• Machiko Isaji

• Masahiro Ito

• Hitoshi Kamiya

• Minoru Sakura

抄録

Humoral and cellular immune responses were examined in 115 children with varicella and in 21 children who had been immunized with live varicella vaccine. Antibody determined with antibody‐dependent cell‐mediated cytotoxicity (ADCC) was detected earlier than neutralizing antibody (NT) in both groups. While humoral and cellular immunity were detected simultaneously in the natural varicella group, cellular immunity was detected earlier than humoral immunity in the immunized group. This suggests that ADCC, rather than NT, is involved in the early stages of recovery from varicella‐zoster virus (VZV) infection.

収録刊行物

• Pediatrics International

  Pediatrics International 33 (1), 43-49, 1991-02

  Wiley

キーワード

• Pediatrics, Perinatology and Child Health

詳細情報

• CRID: 1360292621452351104
• NII論文ID: 30029941230
• NII書誌ID: AA10499234
• DOI: 10.1111/j.1442-200x.1991.tb01518.x
• ISSN: 1442200X
• ISSN: 13288067
• Web Site: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1442-200X.1991.tb01518.x
• Web Site: https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1442-200X.1991.tb01518.x
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  • CiNii Articles