Acquired sideroblastic anaemia during treatment of Wilson's disease with triethylene tetramine dihydrochloride

• Luce Condamine

• Oliver Hermine

• Patrick Alvin

• Martine Levine

• Caroline Rey

• Victor Courtecuisse

抄録

Summary We report one case of acquired sideroblastic anaemia in a patient treated for Wilson's disease with triethylene tetramine dihydrochloride (TTH). No other cause of acquired sideroblastic anaemia was found, and neither iron nor pyridoxine therapy could correct this anaemia. In contrast, decreasing the dose of TTH led to disappearance of ringed sideroblasts. Thus TTH should be added as a further cause of secondary acquired sideroblastic anaemia. The pathophysiology of this finding, probably linked to an abnormality of mitochondrial iron metabolism, is briefly discussed.

収録刊行物

• British Journal of Haematology

  British Journal of Haematology 83 (1), 166-168, 1993-01

  Wiley

キーワード

• Hematology

詳細情報

• CRID: 1361418521270957312
• NII論文ID: 30035650493
• DOI: 10.1111/j.1365-2141.1993.tb04648.x
• ISSN: 13652141
• ISSN: 00071048
• Web Site: https://api.wiley.com/onlinelibrary/tdm/v1/articles/10.1111%2Fj.1365-2141.1993.tb04648.x
• Web Site: https://onlinelibrary.wiley.com/doi/pdf/10.1111/j.1365-2141.1993.tb04648.x
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