展開点自動探索方式を用いた心電図逆問題解法

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  • ECG inverse solution method with an automatic search algorithm for optimal expansion points.
  • テンカイテン ジドウ タンサク ホウシキ オ モチイタ シンデンズ ギャク モ

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This paper describes an advanced ECG inverse solution method with an automatic search algorithm for the expansion points which estimates simultaneously the epicardial potentials and the path of a single moving dipole. First, the initial expansion points were calculated from the measured torso surface potentials using the multipole expansion and moving electrical center methods. Second, the torso surface potentials were estimated during the forward processing with these points using the boundary integral equation relating the torso surface potentials to the epicardial ones. The optimum expansion points were then determined with the simplex method so as to minimize the potential residues between the measured and the estimated torso surface potentials. Thus the epicardial potentials were estimated with a mode expansion and the path of the single moving dipole was determined by linking the optimum expansion points. The validity of this method was examined with an animal experimental system consisting of an isolated canine heart and a cylindrical torso model under normal beats condition and ST elevation produced by a freezing injury. The results are as follows: 1) The average correlation coefficient between measured and estimated epicardial potentials was 0.567 for all the normal QRS, 0.725 during the middle portion of the QRS, and 0.765 for the injured ST elevation. 2) The peak value reproduction ratio of the potentials ranged from 30 to 85 percent for the QRS inverse solution and 85 percent for the ST elevation. 3) The estimated potential distributions fairly agreed with the measured ones, except during the breakthrough period. 4) The average size of the estimated ST elevation was 60 percent of the measured one, and the peak value locations agreed completely with the measured ones. In conclusion, this method can be expected to have sufficient accuracy and supply useful information for the diagnosis of cardiac abnormalities.

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