Chemosensitivity of Established Human Bladder Carcinoma Cell Lines in Vitro

• HISAZUMI Haruo

  Department of Urology, School of Medicine, Kanazawa University

• NAKAJIMA Kazuyoshi

  Department of Urology, School of Medicine, Kanazawa University

• UCHIBAYASHI Tadao

  Department of Urology, School of Medicine, Kanazawa University

書誌事項

タイトル別名

• CHEMOSENSITIVITY OF ESTABLISHED HUMAN BLADDER CARCINOMA CELL LINES <i>IN VITRO</i>
• Chemosensitivity of Established Human B

抄録

The cytotoxic effects of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-nitrosourea hydrochloride, thio-TEPA, 4'-dimethyl-epipodophyllotoxin-β-D-ethylidine glucoside, bleomycin, cis-platinum, mitomycin C, adriamycin and carbazilquinone on asynchronous cells of established human bladder carcinoma lines (KK-47, KW-103 and RT4) were investigated by the in vitro colony formation technique. The dose-survival curves were classified into 2 types: biphasic type (bleomycin) and exponential decrease type (the others). These types and the 50 and 90% growth inhibition doses of the drugs may offer a guide to chemotherapeutic design as well as to the selection of possibly effective agents for bladder cancer therapy.

収録刊行物

• GANN Japanese Journal of Cancer Research

  GANN Japanese Journal of Cancer Research 74 (1), 176-182, 1983

  日本癌学会

キーワード

• Chemosensitivity
• Colony-forming assay
• Human bladder cancer cell lines

詳細情報

• CRID: 1390001205528590592
• NII論文ID: 130006407928
• NII論文ID: 40000529872
• NII書誌ID: AN00045888
• DOI: 10.20772/cancersci1959.74.1_176
• NDL書誌ID: 2623410
• ISSN: 0016450X
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I2623410
• Web Site: https://search.jamas.or.jp/link/ui/1983270567
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可