<i>Fusarium roseum</i> No. 117 (ATCC 28114) 接種米中のラット摂食阻害物質デオキシニバレノールとそのアセテートについて

DOI Web Site 被引用文献2件

書誌事項

タイトル別名
  • Deoxynivalenol and Its Acetate as Feed Refusal Principles in Rice Cultures of <i>Fusarium roseum</i> No. 117 (ATCC 28114)
  • Deoxynivalenol and Its Acetate as Feed
  • Studies on the Toxic Substances in the Infected Cereals (VI)

この論文をさがす

抄録

An attempts was made to elucidate the substances formed in rice cultures of a trichothecene-producing strain of Fusarium roseum No. 117 (ATCC 28114) that caused feed refusal to rats. After 15 days of incubation at 25°C, concentrations of deoxynivalenol (3α, 7α, 15-trihydroxy-12, 13-epoxytrichothec-9-en-8-one, DON) and 3-acetyldeoxynivalenol (3α-acetoxy-7α, 15-dihydroxy-12, 13-epoxytrichothec-9-en-8-one, 3-Ac-DON) reached to about 220μg and about 160μg per g of rice, respectively. Additionally, a trace amount of a new trichothecene, 3α, 15-diacetoxy-7α-hydroxy-12, 13-epoxytrichothec-9-en-8-one was also isolated.<br>The greater part of the feed-refusal activity of the inoculated rice seems to be in the fraction containing above trichothecenes, but participation of other substances was not ruled out. Comparing two-day feed consumption as % of control, medium effective doses of pure DON and 3-Ac-DON were about 100μg and about 150μg per g of feed, respectively. Gain in the body weight of rat was completely inhibited with diets containing 150μg of DON or 200μg of 3-Ac-DON per g, receiving about 4mg of DON or about 7mg of 3-Ac-DON per kg of body weight.

収録刊行物

  • 食品衛生学雑誌

    食品衛生学雑誌 19 (2), 178-184_1, 1978

    公益社団法人 日本食品衛生学会

被引用文献 (2)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ