Serum α<SUB>1</SUB>-Acid Glycoprotein in Cattle with Neoplastic and Inflammatory Diseases

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  • 牛の腫瘍性および炎症性疾患における血清α<SUB>1</SUB>酸性糖蛋白
  • 牛の腫瘍性および炎症性疾患における血清α1酸性糖蛋白
  • ウシ ノ シュヨウセイ オヨビ エンショウセイ シッカン ニ オケル ケッセイ
  • Serum ^|^alpha;1-Acid Glycoprotein in Cattle with Neoplastic and Inflammatory Diseases

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Abstract

The concentrations of serum α1-acid glycoprotein (α1-AGP), sialic acid and mucoprotein were estimated in 145 cattle with neoplastic and inflammatry diseases, and 10 normal cattle. The mean values of serum α1-AGP were 330.5±104.5μg/ml in normal cattle, 897.8±500.8μg/ml in calf type leukemia, 848.3±826.5μg/ml in thymic type leukemia, 1353.2±679.6μg/ml in adult type leukemia, 480.0±353.6gg/ml in skin type leukemia, 4050.0μg/ml in myelocytic leukemia, 702.8±339.4μg/ml in solid tumors, 1065.6±707.4μg/ml in BVD· MD, 1411.8±862.5μg/ml in traumatic pericarditis, 1987.3±1387.1μg/ml in chronic endocarditis, 1471.7±939.5μg/ml in necrotic mastitis and 1107.5±56.4gg/ml in granulocytopathy syndrome.<BR>Serum α1-AGP concentration showed a positive correlation with serum sialic acid and mucoprotein concentration. Serum α1-AGP of necrotic mastitis showed a negative correlation with lymphocyte count, and a positive correlation with serum γ-globulin. As a nonspecific marker, measurement of serum α1-AGP was considered to be useful in the diagnosis of bovine leukosis, solid tumors and inflammatory diseases.

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