Effect of dialysis treatment on glucose metabolism in uremic patients.
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- KANEDA HIROSHI
- Clinic of Renal Disease, Iwaki-Kyoritu General Hospital
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- MIMURA NOBUHIDE
- Department of Nephrology, Toranomon General Hospital
Bibliographic Information
- Other Title
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- Effect of Dialysis Treatment on Glucose
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Abstract
To study the carbohydrate metabolism in uremic patients, the intravenous glucose tolerance test (iv GTT) and insulin sensitivity test were investigated on 69 patients with chronic renal failure, 27 of whom were under the dialysis treatment. 1) Abnormal K-values averaging 1.05 were obtained in uremic patients (creatinine clearance less than 20ml/min). 2) Carbohydrate intolerance in uremic patients was corrected with regular dialysis and the improvement was correlated with the duration of dialyses. 3) The mechanisms of improvement in carbohyd-rate metabolism were different between the short-term dialysis group (less than 12 months of dialysis) and the long-term group (more than 12 months). Enhanced secretion of insulin seemed to be the main cause of this improvement in the former, while the correction of impaired sensitivity to insulin in peripheral tissues in the latter.
Journal
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- The Tohoku Journal of Experimental Medicine
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The Tohoku Journal of Experimental Medicine 122 (1), 35-42, 1977
Tohoku University Medical Press
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Details 詳細情報について
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- CRID
- 1390001204242129408
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- NII Article ID
- 130003407633
- 40005306045
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- NII Book ID
- AA00863920
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- COI
- 1:CAS:528:DyaE2sXksFWhtrc%3D
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- ISSN
- 13493329
- 00408727
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- NDL BIB ID
- 1824385
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- PubMed
- 918954
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed