Aeromonasを分離した急性下痢症の2例

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  • Two Cases of Acute Diarrhea Due to Aeromonas
  • Aeromonas オ ブンリ シタ キュウセイ ゲリショウ ノ 2レイ

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Recently much attention has begun to be paid to aeromonas, a microorganism belonging to Pseudomonadeae with many similarities to enterobacteriaceae. Two patients suffering from acute diarrhea suspicious of bacillary dysentery were examined by the authors in January and August 1961. In both cases a sort of lactose non-fermenting and glucose fermenting, gram negative bacilli was isolated as rich as in pure culture from plate media streaked by stool specimens. The following identification revealed that these bacilli belonged to aeromonas. I Case: Female, 53 years old. Fatigue, vomittings fever of 38.0°C, diarrhea stools with pus, mucus and blood (5 x). A causative food was not detected. After the disappearance of aeromonas due to antibiotic therapy, no relaps was observed. Isolated bacilli demonstrated agglutination with mixed sera of Shigella flexneri obtained. by immunization of rabbit, but not with those of type and group sera, which was attributed to the exsistence of common antigen. The production of agglutintion was not confirmed by agglutination test against the isolated strains using patients' sera. LD5o of aeromonas to mice by intraperitoneal infection was calculated to 0.32 mg. Oral administration of the suspension of 5 mg bacilli to mice resulted neither in abnormal signs nor in isolation of bacilli from organs at the 8th day of the infection. II Case: Male, 18 years old. Lower abdominal pain associated with mucus and bloody diarrhea (5 x), fever to 38.5°C, leucocytosis of 13, 600. Octopus flavored with vinegar was suspected as the source of disease. Some of the isolated strains showed positive reaction by slide agglutination performed with mixed sera of Salmonella and C-2 (0-6, 8) group sera. Two isolated strains were sensi0tive to most antibiotics now available.<BR>Consequently, both geromonas were regarded as causative organism for the glute diarrhea.<BR>It is difficult to distinguish geromonas from enterobacteriaceae by routine tests in clinical laboratory attached to the hospital but cytochrome oxidase test has been known to be useful for this purpose. Consequently, aeromonas should be kept in mind in bacteriological examination of diarrhea stool specimens, a consideration which will prove more important in future.

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