A Method for Determining Deoxyribonucleic Acid Synthetic Time and Mitotic Time of Heart Muscle by Autoradiographic Technique

• Sasaki Rikuro

  Department of Internal Medicine Tohoku University School of Medicine

• Morishita Toshiaki

  Department of Internal Medicine Tohoku University School of Medicine

• Yamagata Shoichi

  Department of Internal Medicine Tohoku University School of Medicine

抄録

A new method to estimate the DNA synthetic time and mitotic time of heart muscle of rats from single autoradiographic specimen was described. If the postsynthetic time is negligible, the DNA synthetic time of heart muscle cells is 15-16 hours in 2-day-old, 1- and 2-week-old rats. The mitotic time of heart muscle cells is 7-11 hours. The DNA synthetic time of interstitial cells is 15-18 hours in 2-day, 1-, 2- and 3-week-old rats. The mitotic time of interstitial cells is 7-9 hours. The DNA synthetic time was also calculated from the estimation of cell number and the results were compared with the above mentioned values. In addition, a method to approach the postsynthetic time was mentioned.

収録刊行物

• The Tohoku Journal of Experimental Medicine

  The Tohoku Journal of Experimental Medicine 100 (1), 15-21, 1970

  東北ジャーナル刊行会

キーワード

• General Biochemistry, Genetics and Molecular Biology
• General Medicine

詳細情報

• CRID: 1390282679216690560
• NII論文ID: 130003491410
• NII論文ID: 40018682172
• NII書誌ID: AA00863920
• DOI: 10.1620/tjem.100.15
• COI: 1:STN:280:DyaE3c7ivVSqug%3D%3D
• ISSN: 13493329
• ISSN: 00408727
• NDL書誌ID: 8507212
• PubMed: 5416551
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I8507212
• Web Site: http://www.jstage.jst.go.jp/article/tjem1920/100/1/100_1_15/_pdf
• 本文言語コード: en
• データソース種別:
  • JaLC
  • NDL
  • Crossref
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可