骨SPECT 定量における異なる校正用線源の相互校正の精度

  • 宮司 典明
    公益財団法人がん研究会有明病院画像診断センター核医学チーム
  • 三輪 建太
    国際医療福祉大学保健医療学部
  • 茂木 一樹
    公益財団法人がん研究会有明病院画像診断センター核医学チーム
  • 梅田 拓朗
    公益財団法人がん研究会有明病院画像診断センター核医学チーム
  • 我妻 慧
    東京都健康長寿医療センター研究所神経画像研究チーム
  • 深井 翔平
    公益財団法人がん研究会有明病院画像診断センター核医学チーム
  • 滝口 智洋
    公益財団法人がん研究会有明病院画像診断センター核医学チーム
  • 寺内 隆司
    公益財団法人がん研究会有明病院画像診断センター核医学チーム
  • 小泉 満
    公益財団法人がん研究会有明病院画像診断センター核医学チーム

書誌事項

タイトル別名
  • Validation of Cross-calibration Schemes for Quantitative Bone SPECT/CT Using Different Sources under Various Geometric Conditions
  • ホネ SPECT テイリョウ ニ オケル コトナル コウセイヨウセン ゲン ノ ソウゴ コウセイ ノ セイド

この論文をさがす

抄録

<p>Purpose: Several cross-calibration schemes have been proposed to produce quantitative values in bone SPECT imaging. Differences in the radionuclide sources and geometric conditions can decrease the accuracy of cross-calibration factor (CCF). The present study aimed to validate the effects of calibration schemes using different sources under various geometric conditions. Methods: Temporal variations as well as variations in acquisition counts and the shapes of 57Co standard and 99mTc point sources and a 99mTc disk source were determined. The effects of the geometric conditions of the source-to-camera distance (SCD) and lateral distance on the CCF were investigated by moving the camera or source away from the origin. The system planar sensitivity of NEMA incorporated into a Symbia Intevo SPECT/CT device (Siemens®) was defined as reference values. Results: The temporal variation in CCF using the 57Co source was relatively stable within the range of 0.7% to 2.3%, whereas the 99mTc source ranged from 2.7% to 7.3%. In terms of source shape, the 57Co standard point source was the most stable. Both SCD and lateral distance decreased as a function of distance from the origin. Errors in the geometric condition were higher for the 57Co standard point source than the 99mTc disk source. Conclusions: Different calibration schemes influenced the reliability of quantitative values. The 57Co standard point source was stable over a long period, and this helped to maintain the quality of quantitative SPECT/CT imaging data. The CCF accuracy of the 99mTc source decreased depending on the preparative method. The method of calibration for quantitative SPECT should be immediately standardized to eliminate uncertainty.</p>

収録刊行物

被引用文献 (2)*注記

もっと見る

参考文献 (23)*注記

もっと見る

関連プロジェクト

もっと見る

詳細情報 詳細情報について

問題の指摘

ページトップへ