Baseline Characteristics of Elderly Japanese Patients Aged ≥75 Years With Non-Valvular Atrial Fibrillation and a History of Stroke ― ANAFIE Registry ―
-
- Kanemaru Kodai
- Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center
-
- Yoshimoto Takeshi
- Department of Neurology, National Cerebral and Cardiovascular Center
-
- Inoue Hiroshi
- Saiseikai Toyama Hospital
-
- Yamashita Takeshi
- The Cardiovascular Institute
-
- Akao Masaharu
- Department of Cardiology, National Hospital Organization Kyoto Medical Center
-
- Atarashi Hirotsugu
- Minami Hachioji Hospital
-
- Ikeda Takanori
- Department of Cardiovascular Medicine, Toho University Faculty of Medicine
-
- Okumura Ken
- Division of Cardiology, Saiseikai Kumamoto Hospital Cardiovascular Center
-
- Koretsune Yukihiro
- National Hospital Organization Osaka National Hospital
-
- Shimizu Wataru
- Division of Cardiology, Nippon Medical School Department of Medicine
-
- Tsutsui Hiroyuki
- Department of Cardiovascular Medicine, Kyushu University Graduate School of Medical Science
-
- Hirayama Atsushi
- Division of Cardiology, Osaka Police Hospital
-
- Yasaka Masahiro
- Department of Cerebrovascular Medicine and Neurology, Cerebrovascular Center, National Hospital Organization Kyushu Medical Center
-
- Yamaguchi Takenori
- National Cerebral and Cardiovascular Center
-
- Teramukai Satoshi
- Department of Biostatistics, Graduate School of Medical Science, Kyoto Prefectural University of Medicine
-
- Kimura Tetsuya
- Medical Science Department, Daiichi Sankyo
-
- Kaburagi Jumpei
- Medical Science Department, Daiichi Sankyo
-
- Takita Atsushi
- Biostatistics & Data Management Department, Daiichi Sankyo
-
- Kusano Kengo
- Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
-
- Toyoda Kazunori
- Department of Cerebrovascular Medicine, National Cerebral and Cardiovascular Center
この論文をさがす
抄録
<p>Background:Despite the well-established benefits in patients with non-valvular atrial fibrillation (NVAF), oral anticoagulants (OAC) have been underused in elderly patients. We investigated the characteristics and status of anti-thrombotic therapy in elderly NVAF patients in Japan according to a history of stroke or of transient ischemic attack (TIA).</p><p>Methods and Results:In a multicenter, prospective, observational study, 32,726 Japanese patients aged ≥75 years with NVAF were enrolled, and divided into 3 groups for the present analysis: 6,543 patients with previous ischemic stroke (IS) or TIA (2,410 women), 275 with previous hemorrhagic stroke (HS; 113 women), and the other 25,908 without previous stroke or TIA (11,470 women). Median CHADS2score was 5 in patients with IS/TIA, 2 in those with HS and 2 in those without stroke/TIA (P<0.05). Anti-thrombotic agents were used in 97.1% of patients with IS/TIA (OAC alone in 73.0%; antiplatelets alone in 3.7%; and both in 23.4%), 90.2% of those with HS (84.7%, 3.2%, and 12.1%, respectively), and 94.1% of those without stroke/TIA (83.4%, 2.7%, and 13.9%, respectively; P<0.05 for any anti-thrombotic choice). Of patients taking OAC, 72.2% received direct OAC (DOAC).</p><p>Conclusions:In this unique nationwide NVAF registry of >30,000 elderly patients, >90% of patients, even those with HS, received anti-thrombotic therapy, nearly always with OAC. DOAC were the major choice of OAC.</p>
収録刊行物
-
- Circulation Journal
-
Circulation Journal 84 (3), 516-523, 2020-02-25
一般社団法人 日本循環器学会
- Tweet
詳細情報 詳細情報について
-
- CRID
- 1390565134830976768
-
- NII論文ID
- 130007801790
-
- NII書誌ID
- AA11591968
-
- ISSN
- 13474820
- 13469843
-
- NDL書誌ID
- 030282244
-
- PubMed
- 31983727
-
- 本文言語コード
- en
-
- データソース種別
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- 抄録ライセンスフラグ
- 使用不可