Enzymatic studies on aromatic prenyltransferases

• Takahiro Mori

Abstract

Aromatic prenyltransferases (PTases), including ABBA-type and dimethylallyl tryptophan synthase (DMATS)-type enzymes from bacteria and fungi, play important role for diversification of the natural products and improvement of the biological activities. For a decade, the characterization of enzymes and enzymatic synthesis of prenylated compounds by using ABBA-type and DMATS-type PTases have been demonstrated. Here, I introduce several examples of the studies on chemoenzymatic synthesis of unnatural prenylated compounds and the enzyme engineering of ABBA-type and DMATS-type PTases.

Journal

• Journal of natural medicines / The Japanese Society of Pharmacognosy

  Journal of natural medicines / The Japanese Society of Pharmacognosy 74 (3), 501-512, 2020

  Tokyo : Springer Japan Production Department

Keywords

• Biosynthesis
• Enzyme engineering
• Aromatic prenyltransferase
• Prenylated compounds

Details

• CRID: 1523951030187588096
• NII Article ID: 40022252768
• NII Book ID: AA12114658
• ISSN: 13403443
• ISSN: 18610293
• DOI: 10.1007/s11418-020-01393-x
• NDL BIB ID: 030449279
• Web Site: http://id.ndl.go.jp/bib/030449279
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I030449279
• Web Site: http://link.springer.com/content/pdf/10.1007/s11418-020-01393-x.pdf
• Web Site: http://link.springer.com/article/10.1007/s11418-020-01393-x/fulltext.html
• Web Site: https://search.jamas.or.jp/link/ui/2021123654
• Text Lang: en
• NDL Source Classification:
  • ZS51(科学技術--薬学)
• Data Source:
  • NDL
  • Crossref
  • CiNii Articles
  • KAKEN