The Ability of Nutrition to Mitigate Epigenetic Drift: A Novel Look at Regulating Gene Expression

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  • D. PALMER Raymond
    Helium-3 Biotech
  • PAPA Veronica
    Department of Motor Sciences and Wellness, University of Naples “Parthenope” FABAP Research Center
  • VACCAREZZA Mauro
    Curtin Medical School, Faculty of Health Sciences, Curtin Health Innovation Research Institute (CHIRI), Curtin University Department of Translational Medicine, University of Ferrara

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Abstract

<p>Epigenetic drift causes modification in gene expression during aging and a myriad of physiological changes that are mostly undesirable, remove youthful phenotype and are related to biological decay and disease onset. The epigenome is considered a stable regulator of genetic expression. Moreover, evidence is now accumulating that commonly available compounds found in foods can influence the epigenome to embrace a more youthful and therefore, more disease resistant state. Here we explore the correlation between nutriment and the epigenetic regulation through various types of alimentation. The aim is not to discuss specific chemicals involved in disease onset. Instead, we offer a brief glance at pathogens and offer a practical pathway into epigenetic regulation, hypothesizing that epigenetic drift might be attenuated by several foods able to drive a more youthful and disease resistant phenotype.</p>

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