Studies on behavior of protein kinase C in transformed NIH3T3 cells NIH3T3形質転換細胞におけるプロテインキナーゼCに関する研究
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著者
書誌事項
- タイトル
-
Studies on behavior of protein kinase C in transformed NIH3T3 cells
- タイトル別名
-
NIH3T3形質転換細胞におけるプロテインキナーゼCに関する研究
- 著者名
-
大内田, 守
- 著者別名
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オオウチダ, マモル
- 学位授与大学
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九州大学
- 取得学位
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理学博士
- 学位授与番号
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甲第2873号
- 学位授与年月日
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1991-12-25
注記・抄録
博士論文
目次
- CONTENTS / p2 (0003.jp2)
- SUMMARY / p4 (0005.jp2)
- LIST OF ABBREVIATIONS / p6 (0007.jp2)
- INTRODUCTION / p7 (0008.jp2)
- 1.Oncogene / p7 (0008.jp2)
- 2.Protein Kinase C / p10 (0011.jp2)
- 3.80K Protein / p13 (0014.jp2)
- MATERIALS AND METHODS / p14 (0015.jp2)
- 1.Materials / p14 (0015.jp2)
- 2.Methods / p14 (0015.jp2)
- RESULTS / p22 (0023.jp2)
- 1.Identification of the 80K Protein / p22 (0023.jp2)
- 2.Reduction of the Phosphorylation of 80K Protein in Transformants but not Normal NIH3T3 Cells / p22 (0023.jp2)
- 3.Establishment of Hormone-Inducible H-ras Transformants / p24 (0025.jp2)
- 4.Reduction of the Phosphorylation of 80K Protein in Inducible H-ras Transformant / p26 (0027.jp2)
- 5.Different Distribution of Protein Kinase C Activity between Normal and Transformed NIH3T3 Cells / p26 (0027.jp2)
- 6.Analysis of mRNA in Early Stage of Cellular Transformation / p27 (0028.jp2)
- 7.Effects of Inhibition of Protein Kinase C on Cell Growth and on Anchorage-independent Growth / p28 (0029.jp2)
- 8.Mobility Shift Assay / p29 (0030.jp2)
- DISCUSSION / p32 (0033.jp2)
- 1.Reduction of the Phosphorylation of 80K Protein in Transformants / p32 (0033.jp2)
- 2.in vitro Activity of Protein Kinase C / p37 (0038.jp2)
- 3.Change of Protein Kinase C in Early Stage of Transformation / p39 (0040.jp2)
- 4.Cellular Transformation and Behavior of Protein Kinase C / p42 (0043.jp2)
- ACKNOWLEDGEMENTS / p48 (0049.jp2)
- REFERENCES / p49 (0050.jp2)
- FIGURES / p63 (0064.jp2)
- TABLES / p85 (0086.jp2)