Induction of antibodies against pathogenic microbes with anti-idiotype antibodies 抗イディオタイプ抗体による病原微生物に対する抗体の誘導
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著者
書誌事項
- タイトル
-
Induction of antibodies against pathogenic microbes with anti-idiotype antibodies
- タイトル別名
-
抗イディオタイプ抗体による病原微生物に対する抗体の誘導
- 著者名
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田中, 雅之
- 著者別名
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タナカ, マサユキ
- 学位授与大学
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北海道大学
- 取得学位
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博士 (獣医学)
- 学位授与番号
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乙第4198号
- 学位授与年月日
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1992-12-25
注記・抄録
博士論文
目次
- CONTENTS / (0003.jp2)
- 1. GENERAL INTRODUCTION / p1 (0006.jp2)
- 2. Part 1 : Induction of Antibodies against Newcastle Disease Virus with Murine Polyclonal Anti-idiotype Antibodies in Mice and Chickens / p3 (0008.jp2)
- INTRODUCTION / p4 (0009.jp2)
- MATERIALS AND METHODS / p5 (0010.jp2)
- RESULTS / p8 (0013.jp2)
- Anti-Id antibodies induced with anti-NDV MAbs / p8 (0013.jp2)
- Cross-reactivity of anti-Id antibodies with heterologous anti-NDV antibodies / p11 (0016.jp2)
- Induction of anti-viral antibodies by immunization with polyclonal anti-Id antibodies / p12 (0017.jp2)
- Protective effect of anti-Id antibodies immunization in chickens / p16 (0021.jp2)
- DISCUSSION / p17 (0022.jp2)
- SUMMARY / p19 (0024.jp2)
- 3. Part II : Induction of Anti-Theileria sergenti Antibodies with Murine Monoclonal Anti-idiotype Antibodies in Mice and Calves / p20 (0025.jp2)
- INTRODUCTION / p21 (0026.jp2)
- MATERIALS AND METHODS / p22 (0027.jp2)
- RESULTS / p26 (0031.jp2)
- Production and characterization of monoclonal anti-Id hybridoma cells / p26 (0031.jp2)
- Cross-reactivity of anti-Id antibodies with heterologous anti-T. sergenti antibodies / p28 (0033.jp2)
- Induction of anti-T. sergenti antibodies by immunization with anti-Id MAb in mice / p29 (0034.jp2)
- Anti-anti-Id antibodies induced with anti-Id MAb-Fab in calves / p31 (0036.jp2)
- Changes in haematological findings, antibody titers and macrophage activities / p32 (0037.jp2)
- DISCUSSION / p35 (0040.jp2)
- SUMMARY / p38 (0043.jp2)
- 4.CONCLUSION / p39 (0044.jp2)
- 5.ACKNOWLEDGEMENTS / p41 (0046.jp2)
- 6.REFERENCES / p42 (0047.jp2)