Studies on the structure and function of aspartic proteinases アスパラギン酸プロテアーゼの構造と機能に関する研究
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著者
書誌事項
- タイトル
-
Studies on the structure and function of aspartic proteinases
- タイトル別名
-
アスパラギン酸プロテアーゼの構造と機能に関する研究
- 著者名
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Athauda, Senarath B. P
- 著者別名
-
アタウダ, セナラッツ バンダーラ パラシクラマ
- 学位授与大学
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東京大学
- 取得学位
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博士 (理学)
- 学位授与番号
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甲第9389号
- 学位授与年月日
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1992-03-30
注記・抄録
博士論文
目次
- CONTENTS / p3 (0005.jp2)
- ACKNOWLEDGMENTS / p1 (0003.jp2)
- CONTENTS / p3 (0005.jp2)
- ABBREVIATIONS / p6 (0008.jp2)
- 1 GENERAL INTRODUCTION TO ASPARTIC PROTEINASES / (0009.jp2)
- 1.Introduction / p1 (0010.jp2)
- 2.Biologicalsources / p2 (0011.jp2)
- 3.Characteristic properties of aspartic proteinases / p2 (0011.jp2)
- 4.Catalytic mechanism / p7 (0016.jp2)
- 5.Importance of aspartic proteinases / p8 (0017.jp2)
- 6.Brief description of the present study / p9 (0018.jp2)
- 2 HUMAN PEPSINOGENS AND PEPSINS.PURIFICATION,CHARACTERIZATION AND SOME STRUCTURAL DIFFERENCES AMONG ISOZYMOGENS AND ISOZYMES / (0020.jp2)
- 1.Introduction / p11 (0021.jp2)
- 2.Experimental procedures / p16 (0026.jp2)
- 3.Results / p25 (0035.jp2)
- 4.Discussion / p54 (0064.jp2)
- 3 HUMAN PROCATHEPSIN E AND CATHEPSIN E.PURIFICATION AND CHARACTERIZATION AND THEIR STRUCTURAL DIFFERENCES / (0070.jp2)
- 1.Introduction / p60 (0071.jp2)
- 2.Experimental procedures / p65 (0076.jp2)
- 3.Results / p71 (0082.jp2)
- 4.Discussion / p106 (0117.jp2)
- 4 PROTEOLYTIC ACTIVITIES OF ASPARTIC PROTEINASES AT THE NEUTRAL pH / (0126.jp2)
- 1.Introduction / p115 (0127.jp2)
- 2.Experimental procedures / p119 (0131.jp2)
- 3.Results / p121 (0133.jp2)
- 4.Discussion / p137 (0149.jp2)
- 5 INHIBITION OF ASPARTIC PROTEINASES BY α₂ -MACROG-LOBULIN AND STRUCTURAL CHANGES IN THE INHIBITOR / (0151.jp2)
- 1.Introduction / p139 (0152.jp2)
- 2.Experimental procedures / p146 (0159.jp2)
- 3.Results / p150 (0163.jp2)
- 4.Discussion / p202 (0215.jp2)
- 6 PURIFICATION AND CHARACTERIZATION OF DROSOPHILA COPIA PROTEINASE EXPRESSED IN E.COLI AND ITS ACTIVE SITE MUTAGENESIS / (0222.jp2)
- 1.Introduction / p209 (0223.jp2)
- 2.Experimental procedures / p219 (0233.jp2)
- 3.Results / p230 (0244.jp2)
- 4.Discussion / p263 (0277.jp2)
- 7 Conclusions / p268 (0283.jp2)
- 8 REFERENCES / p272 (0288.jp2)